If the COVID-19 pandemic taught us anything, it's that there is nothing wrong with good hygiene. Of course, many people like to maintain a high standard of hygiene while traveling. Unfortunately, hotels aren't always the cleanest of places. Despite housekeeping's best efforts, things like TV remotes aren't frequently disinfected. So, if you'd prefer to enjoy a higher level of cleanliness during your stay, wet wipes and plastic wraps are your friends.
There are two options here. First, you can do a quick antibacterial wipe-down with some disinfectant wipes. If this seems like too much work, you could instead use plastic wrap to enclose things you rather not touch.